ISO/TS TECHNICAL SPECIFICATION 21361 First edition 2019-04 Nanotechnologies Method to quantify air concentrations of carbon black and amorphous silica in the nanoparticle size range in a mixed dust manufacturing environment Nanotechnologies ( Quantification du noir de carbonne et de la silice amorphe nanométriques en suspension dans I'air en ambiance de production Reference number ISO/TS 21361:2019(E) ISO @ IS0 2019 IS0/TS 21361:2019(E) COPYRIGHTPROTECTEDDOCUMENT @ ISO 2019 All rights reserved. Unless otherwise specified, or required in the context of its implementation, no part of this publication may be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying, or posting on the internet or an intranet, without prior written permission. Permission can be requested from either IsO at the address below or Iso's member body in the country of the requester. ISO copyright office CP 401 : Ch. de Blandonnet 8 CH-1214 Vernier, Geneva Phone: +4122 749 0111 Fax: +41 22 749 09 47 Email: [email protected] Website: www.iso.org Published in Switzerland ii @ IS0 2019 - All rights reserved IS0/TS 21361:2019(E) Contents Page Foreword ..iv Introduction. ..V 1 Scope. ...1 2 Normative references 3 Terms and definitions 4 Principle 5 Abbreviations. 6 Reagents 7 Apparatus ..4 7.1 Air sampling - Equipment and consumable supplies ..4 7.1.1 Electrical low cascade pressure impactor (ELPCI) .4 7.1.2 Limit of Detection. .4 7.1.3 Real-time aerosol monitor. .5 7.1.4 Vacuum pump. 5 7.1.5 Polycarbonate substrate .5 7.1.6 Hydrocarbon grease. 5 7.2 Analytical/microscopy laboratories. .6 7.3 Sample analysis Equipment and consumables .6 7.3.1 Transmission electron microscope (TEM) .. 6 7.3.2 Energy dispersive spectrometry (EDS) .6 7.3.3 Computer. ..6 7.3.4 TEM Grid ..6 8 Air sample collection .6 8.1 Preparation for sampling .6 8.2 Determination of sampling time ..7 8.3 Sample collection procedure .7 9 Procedure for analysis .7 9.1 General .7 9.2 Preparation of substrates .8 9.3 Sample analysis. 9.3.1 Instrument conditions ..8 9.3.2 Data collection. 9.4 Calculation of air concentration ..9 10 Uncertainties and performance criteria ..10 10.1 Particle counting with the ELPCI. .10 10.2 Particle analysis with TEM/EDS ..11 11 Test report .11 Annex A (informative) Case study overview ..12 Bibliography ..13 IS0 2019 - All rights reserved iii