ISO/ASTM52303:2015(E) An American National Standard Standard Guide for Absorbed-Dose Mapping in Radiation Processing Facilities1 This standard is issued under the fixed designa ation ISO/ASTM52303; the I year of original adoption or, in the case of revision, the year of last revision. 1. Scope E178 Practice for Dealing With Outlying Observations 1.1 This document provides guidance in determining E2232 Guide for Selection and Use of Mathematical Meth- absorbed-dose distributions (mapping) in products, materials ods for Calculating Absorbed Dose in Radiation Process- or substances irradiated in gamma, X-ray (bremsstrahlung) and ing Applications electron beam facilities. 2.2 ISO/ASTM Standards.:2 NoTe 1For irradiation of food and the radiation sterilization of health 51261 Guide for Selection and Calibration of Dosimetry care products, specific ISO and ISO/ASTM standards containing dose Systems for Radiation Processing mapping requirements exist.See ISO/ASTMPractices 51431,51608 51431 Practice for Dosimetry in Electron Beam and X-Ray 51649, 51702 and 51818 and ISO 11137-1. Regarding the radiation sterilization of health care products, in those areas covered by ISO (Bremsstrahlung) Irradiation Facilities for Food Process- 11137-1, that standard takes precedence. ing 51608 Practice for Dosimetry in an X-ray (Bremsstrahlung) 1.2 This guide is one of a set of standards that provides Facility for Radiation Processing recommendations for properly implementing dosimetry in 51649 Practice for Dosimetry in an Electron Beam Facility radiationprocessing.it is intended to be read in conjunction for Radiation Processing at Energies between 300 keV and withISO/ASTM52628 25MeV 1.3 Methods of analyzing the dose map data are described. 51702 Practice for Dosimetry in a Gamma Irradiation Facil- Examples are provided of statistical methods that may be used ity for Radiation Processing to analyzedose map data. 51707 Guide for Estimating Uncertainties in Dosimetry for 1.4 Dose mapping for bulk flow processing and fluid Radiation Processing streams is not discussed. 51818 Practice for Dosimetry in an Electron Beam Facility for Radiation Processing at Energies between 80 and 300 1.5 Dosimetry is an element of a total quality management keV system for an irradiation facility. Other controls besides do- 52628 Practice for Dosimetry in Radiation Processing simetry may be required for specific applications such as medical device sterilization and food preservation. 2.3 International Commission on Radiation Units and Mea- surements Reports:3 1.6 This standard does not purport to address all of the ICRU Report 85a Fundamental Quantities and Units for safety concerns, if any, associated with its use. It is the Ionizing Radiation responsibility of the user of this standard to establish appro- 2.4 International Organization for Standardization:4 priate safety and health practices and determine the applica- ISO 11137-1 Sterilization of health care products - Radia- bility of regulatory requirements prior to use. tion - Part 1: Requirements for development, validation, 2. Referenced Documents and routine control of a sterilization process for medical 2.1 ASTM Standards:? devices 2.5 Joint Committee for Guides in Metrology (JCGM) E170 Terminology Relating to Radiation Measurements and Dosimetry Reports.: JCGM 100:2008 GUM 1995, with minor corrections, Evaluation of measurement data Guidetotheexpression IThis guide is under the jurisdiction of ASTM Committee E61 on Radiation of uncertainty in measurement Processing and is the direct responsibility of Subcommittee E61.03 on Dosimetry Application and is also under the jurisdiction of ISO/TC 85/WG 3. urrentedition published as ASTM E2303-03. Last previous ASTM edition E2303-115i. The 3 Available from International Commission on Radiation Units and present International Standard ISO/ASTM 52303-2015(E) replaces ASTM Measurements,7910Woodmont Ave.,Suite 800,Bethesda,MD20814. E23031181 4 Available from International Orga